| Recommendations for treatment of hospital-acquired and ventilator-associated pneumonia: review of recent international guidelines. | |
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MedLine Citation:
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PMID: 20597671 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recently published guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia are reviewed for recommendations regarding diagnosis and antimicrobial therapy to assess the implications for development of future clinical trials. Despite some differences (mostly related to likely pathogens), there is a general agreement about the recommended approach to management. All of the reviewed guidelines invariably recommend early, appropriate antimicrobial therapy and avoidance of excessive antimicrobials by deescalation of therapy on the basis of microbiological culture results and the clinical response of the patient. Developers of future clinical trials will need to be mindful of these recommendations to maintain best practice care for each investigator. |
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Authors:
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Thomas M File |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 51 Suppl 1 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-05 Completed Date: 2010-11-08 Revised Date: 2011-02-02 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: S42-7 Citation Subset: IM |
Affiliation:
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Northeastern Ohio Universities College of Medicine, Rootstown, and Summa Health System, Akron, Ohio, USA. FileT@summa-health.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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therapeutic use* Bacteria / drug effects, isolation & purification Clinical Trials as Topic Cross Infection / diagnosis, drug therapy* Hospitals Humans Microbial Sensitivity Tests Pneumonia, Bacterial / diagnosis, drug therapy* Pneumonia, Ventilator-Associated / diagnosis, drug therapy* Practice Guidelines as Topic* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
| Comments/Corrections | |
Erratum In:
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Clin Infect Dis. 2010 Nov 1;51(9):1114 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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