Document Detail

Recommendations for management of antiplatelet therapy in patients undergoing elective noncardiac surgery after coronary stent implantation.
MedLine Citation:
PMID:  23149359     Owner:  NLM     Status:  MEDLINE    
Patients commonly undergo noncardiac surgical procedures after implantation of a coronary stent. In the case where surgery cannot be deferred until completing the minimum duration of dual antiplatelet therapy, the Brigham and Women's Hospital Cardiac Catheterization Laboratory recommends using a glycoprotein IIb/IIIa bridging protocol to minimize the risk of perioperative ischemic events. We discuss our algorithm for managing antiplatelet agents, including the newer agents, prasugrel and ticagrelor, in patients undergoing noncardiac surgery after coronary stenting and present our glycoprotein IIb/IIIa bridging strategy along with a review of the relevant pharmacodynamic and clinical evidence.
Pei-Hsiu Huang; Kevin J Croce; Deepak L Bhatt; Frederic S Resnic
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical pathways in cardiology     Volume:  11     ISSN:  1535-2811     ISO Abbreviation:  Crit Pathw Cardiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-15     Completed Date:  2013-05-24     Revised Date:  2013-12-24    
Medline Journal Info:
Nlm Unique ID:  101165286     Medline TA:  Crit Pathw Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  177-85     Citation Subset:  IM    
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MeSH Terms
Adenosine / administration & dosage,  adverse effects,  analogs & derivatives*
Administration, Oral
Coronary Disease / surgery
Piperazines / administration & dosage*,  adverse effects
Platelet Aggregation Inhibitors / administration & dosage*,  adverse effects
Platelet Glycoprotein GPIIb-IIIa Complex
Practice Guidelines as Topic
Purinergic P2Y Receptor Antagonists / administration & dosage*,  adverse effects
Risk Assessment
Risk Factors
Surgical Procedures, Elective*
Thiophenes / administration & dosage*,  adverse effects
Reg. No./Substance:
0/Piperazines; 0/Platelet Aggregation Inhibitors; 0/Platelet Glycoprotein GPIIb-IIIa Complex; 0/Purinergic P2Y Receptor Antagonists; 0/Thiophenes; 0/Ticagrelor; 34K66TBT99/prasugrel; K72T3FS567/Adenosine
Erratum In:
Crit Pathw Cardiol. 2013 Sep;12(3):175
Note: Dosage error in article text

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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