| Recombinant granulocyte-macrophage colony-stimulating factor in the treatment of indolent ulcers with Klippel-Trénaunay-Weber syndrome: a case report. | |
| | |
MedLine Citation:
|
PMID: 17336199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Klippel-Trénaunay-Weber syndrome (KTWS) is a rare congenital disease characterized by cutaneous hemangiomata, venous varicosities and osseous soft tissue hypertrophy of the affected limb. We report a case of a patient with KTWS who had developed severe chronic, non-healing cutaneous ulcers resulting from several angiography procedures with embolization by various agents. The ulcers were treated with perilesional granulocyte-macrophage colony-stimulating-factor (GM-CSF) with gratifying results. This case report suggests that GM-CSF may enhance the healing of chronic wounds not responding to other treatment modalities in patients with congenital angiodystrophy syndromes, thus salvaging a limb from amputation. |
| | |
Authors:
|
Furqan H Siddiqui; Moinuddin H Mokhashi; Abdullah Boathman |
Related Documents
:
|
3282059 - Proteus syndrome: ocular complications. 18285739 - Overlapping of sturge weber syndrome and klippel trenaunay weber syndrome. 17914149 - Bryan artificial cervical disc arthroplasty in a patient with klippel-feil syndrome. 2288389 - Crossed cerebellar diaschisis in the sturge-weber syndrome. 12590699 - Cobb syndrome in an infant: treatment with endovascular embolization and corticosteroid... 6327979 - Congenital dysplastic angiopathy (klippel-trenaunay-weber syndrome) with vulvar involve... 18805359 - Leigh and leigh-like syndrome in children and adults. 8646439 - 'seronegative' sjögren's syndrome manifested as a subset of chronic fatigue syndrome. 17389129 - Neurodevelopmental and behavioral issues in williams syndrome. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of pediatric surgery Volume: 42 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2007 Mar |
Date Detail:
|
Created Date: 2007-03-05 Completed Date: 2007-04-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 558-60 Citation Subset: IM |
Affiliation:
|
Research Integrity Office, University of Louisville Hospital, Louisville, KY 40202, USA. furqansi@ulh.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Child Female Granulocyte Macrophage Colony-Stimulating Factors, Recombinant / pharmacology, therapeutic use* Humans Klippel-Trenaunay-Weber Syndrome / complications* Leg Ulcer / drug therapy*, etiology Wound Healing / drug effects |
| Chemical | |
Reg. No./Substance:
|
0/Granulocyte Macrophage Colony-Stimulating Factors, Recombinant |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pelvic osteomyelitis: a diagnostic challenge in children.
Next Document: Perivascular epithelioid cell tumour of the vagina in an 8 year old girl.