| Recent trends in specular light reflectance beyond clinical fluorescence diagnosis. | |
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MedLine Citation:
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PMID: 21411414 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Under specific light illumination, particularly ultraviolet (UV) and near-UV light stimulation, the skin produces both specular light reflectance and, possibly, specific fluorescent emission. These properties offer diagnostic clues and disclose some peculiar functions of the skin. A series of superficial infections (erythrasma, some tinea capitis types, tinea/pityriasis versicolor, dermatophytoses, etc.) and pilosebaceous follicles enriched in Propionibacterium spp show fluorescence. This latter characteristic is downgraded or lost while on some anti-acne treatments. A quenching effect of fluorescence is observed following the application of sunscreens. The (pre)neoplastic areas prepared for methylaminolevulinate photodynamic therapy (MAL-PDT) show reddish fluorescence following drug metabolisation producing porphyrins by the abnormal activated cells. Of note, when using a recording sensitive CCD camera instead of casual visual observation, skin fluorescence may be superimposed on the specular reflectance of the incident light. With the current technology, these situations are not distinguished with confidence. Any harsh and scaly lesion appears brighter following yellowish specular light reflectance. Stratum corneum samplings collected on clear self-adhesive discs or cyanoacrylate skin surface strippings are conveniently examined ex vivo, taking advantage of the same optical properties. |
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Authors:
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Grégory Szepetiuk; Sébastien Piérard; Claudine Pierard-Franchimont; Marie Caucanas; Pascale Quatresooz; Gérald E Pierard |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-16 |
Journal Detail:
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Title: European journal of dermatology : EJD Volume: - ISSN: 1167-1122 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9206420 Medline TA: Eur J Dermatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Laboratory of Skin Bioengineering and Imaging, Department of Dermatopathology, University Hospital Sart Tilman, Liège, Belgium. |
Vernacular Title:
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Recent trends in specular light reflectance beyond clinical fluorescence diagnosis. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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