Document Detail


Recent progress in facial paralysis: advances and obstacles.
MedLine Citation:
PMID:  20625294     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: Facial paralysis is a devastating and debilitating condition for which a range of management options exists; all of them continue to have limitations. We review the recent scientific literature and highlight key developments and opportunities for further exploration with the goal that this may help direct clinical practice and research endeavor. RECENT FINDINGS: We reviewed recent findings in the evaluation of facial paralysis, pharmacological management, nerve injury prevention and treatment. This includes review of novel techniques using photography and videography. Review of surgical and adjunctive techniques identifies several refinements of existing techniques, some novel techniques, and the value of adjunctive materials and therapies. SUMMARY: Management of facial paralysis remains an area of active investigation and innovation. The challenge to researchers and care providers will be to continue to explore and refine management strategies while maintaining rigorous and standardized means of evaluation and follow-up, such that outcomes may be determined and reported accurately and in a way that they can be transferred to other clinical practices. Further study of the role of growth factors and stem cells in facial nerve regeneration is critical, and is the most likely means of surmounting the remaining barriers to successful outcomes in alleviating the ravages of this devastating malady.
Authors:
Maya G Sardesai; Kriss Moe
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Publication Detail:
Type:  Historical Article; Journal Article; Review    
Journal Detail:
Title:  Current opinion in otolaryngology & head and neck surgery     Volume:  18     ISSN:  1531-6998     ISO Abbreviation:  Curr Opin Otolaryngol Head Neck Surg     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-15     Completed Date:  2010-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9417024     Medline TA:  Curr Opin Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  266-71     Citation Subset:  IM    
Affiliation:
Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology - Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Botulinum Toxins / therapeutic use
Electromyography
Facial Expression
Facial Muscles / surgery
Facial Nerve / pathology,  physiology
Facial Nerve Injuries
Facial Paralysis / history,  therapy*
Glucocorticoids / history,  therapeutic use
History, Ancient
Humans
Injury Severity Score
Intraoperative Complications / prevention & control
Monitoring, Intraoperative
Nerve Growth Factors / therapeutic use
Nerve Transfer
Neuromuscular Agents / therapeutic use
Nitric Oxide Synthase / antagonists & inhibitors
Peripheral Nerves / transplantation
Photogrammetry
Physical Therapy Modalities
Reflex
Regeneration
Stem Cell Transplantation
Chemical
Reg. No./Substance:
0/Botulinum Toxins; 0/Glucocorticoids; 0/Nerve Growth Factors; 0/Neuromuscular Agents; EC 1.14.13.39/Nitric Oxide Synthase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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