Document Detail


Recent pathogenic aspects in essential hypertension and hypertension associated with diabetes mellitus.
MedLine Citation:
PMID:  7453095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The sympathetic system, the body sodium-fluid volume state, the renin-angiotensin system, functional and structural characteristics of the heart and blood vessels, and some other components are important complementary factors in blood pressure regulation. A deviation from the normal equilibrium among these components, with a persisting non-physiologic increase in pressor factor(s) or in the basal vascular tone and/or cardiovascular reactivity to pressor factors, leads to hypertension. This review discusses recent observations and concepts regarding the pathogenesis of essential hypertension and hypertension associated with diabetes mellitus. It focuses on the roles of various pressor factors as well as cardiovascular pressor responsiveness in the genesis of high blood pressure and in the antihypertensive mechanism of diuretic treatment.
Authors:
P Weidmann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  58     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1981-03-27     Completed Date:  1981-03-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  1071-89     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular System / physiopathology
Diabetes Complications*
Hemodynamics
Humans
Hypertension / etiology,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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