Document Detail

Recent intervention trials in hypertension initiated in Sweden--HOT, CAPPP and others. Hypertension Optimal Treatment Study. Captopril Prevention Project.
MedLine Citation:
PMID:  10423077     Owner:  NLM     Status:  MEDLINE    
In 1998 the final results were presented of two large intervention trials in hypertension, the Hypertension Optimal Treatment Study (HOT) and the Captopril Prevention Project (CAPPP). Both were initiated from Sweden although the HOT Study was conducted in 26 countries worldwide and the CAPPP Study in Finland and Sweden. The HOT and CAPPP trials and their principal results will be reviewed briefly here. In addition a brief up-date will be provided of three ongoing intervention trials in hypertension that were also initiated from Sweden: the Swedish Trial in Old Patients with Hypertension-2 (STOP-Hypertension-), the Nordic Diltiazem (NORDIL) Study and the Study on Cognition and Prognosis in Elderly Hypertensives (SCOPE).
L Hansson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical and experimental hypertension (New York, N.Y. : 1993)     Volume:  21     ISSN:  1064-1963     ISO Abbreviation:  Clin. Exp. Hypertens.     Publication Date:    1999 Jul-Aug
Date Detail:
Created Date:  1999-12-01     Completed Date:  1999-12-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9305929     Medline TA:  Clin Exp Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  507-15     Citation Subset:  IM    
Department of PublicHealth and Social Sciences: Geriatrics, University of Uppsala, Sweden.
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use
Aged, 80 and over
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Aspirin / therapeutic use
Blood Pressure*
Calcium Channel Blockers / therapeutic use
Captopril / therapeutic use
Cardiovascular Diseases / mortality,  prevention & control*
Clinical Trials as Topic
Felodipine / therapeutic use
Hypertension / drug therapy*
Isradipine / therapeutic use
Middle Aged
Randomized Controlled Trials as Topic
Stroke / prevention & control
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Calcium Channel Blockers; 50-78-2/Aspirin; 62571-86-2/Captopril; 72509-76-3/Felodipine; 75695-93-1/Isradipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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