| Recent developments in urologic oncology: positron emission tomography molecular imaging. | |
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MedLine Citation:
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PMID: 18391633 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE OF REVIEW: Traditional morphologically based imaging modalities in uro-oncology are now being complemented by the functional and molecular imaging technique positron emission tomography (PET). This review highlights the most important recent developments. RECENT FINDINGS: Prostate cancer: PET imaging with the new radiotracers 11C-choline, 18F-fluorocholine, and 11C-acetate show promising results. The role of anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid remains to be elucidated further. 18F-fluoride PET is useful for the detection of bone metastases. Bladder cancer: 18F-fluorodeoxyglucose (FDG) PET/CT with delayed images after a diuretic and oral hydration may improve detection of locally recurrent or residual bladder tumours. Both 18F-FDG PET and 11C-choline PET may be useful for staging of bladder cancer. Renal cancer: 18F-FDG PET has a role in staging and restaging of the disease. Recently, 124I-cG250 PET has shown promising results in the detection of clear-cell renal carcinoma. Testicular cancer: 18F-FDG PET is useful in staging and follow-up after treatment. There are no important recent developments with new radiopharmaceuticals in testicular cancer. SUMMARY: The utility of PET molecular imaging in uro-oncology expanded due to the new metabolic PET tracers with more favourable properties. |
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Authors:
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Kirsten Bouchelouche; Peter Oehr |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in oncology Volume: 20 ISSN: 1531-703X ISO Abbreviation: Curr Opin Oncol Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-04-08 Completed Date: 2008-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9007265 Medline TA: Curr Opin Oncol Country: United States |
Other Details:
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Languages: eng Pagination: 321-6 Citation Subset: IM |
Affiliation:
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PET & Cyclotron Unit, Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark. bouchelouche@mail.tele.dk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Carbon Radioisotopes
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diagnostic use Female Fluorodeoxyglucose F18 / diagnostic use Humans Kidney Neoplasms / radionuclide imaging* Male Neoplasm, Residual / radionuclide imaging Positron-Emission Tomography* / methods Prostatic Neoplasms / radionuclide imaging* Radioisotopes / diagnostic use Radiopharmaceuticals / diagnostic use Testicular Neoplasms / radionuclide imaging* Urinary Bladder Neoplasms / radionuclide imaging* |
| Chemical | |
Reg. No./Substance:
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0/Carbon Radioisotopes; 0/Radioisotopes; 0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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