| Recent developments in the design and synthesis of hybrid molecules based on aminoquinoline ring and their antiplasmodial evaluation. | |
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MedLine Citation:
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PMID: 19361896 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A short history of hybrid molecules based on aminoquinolines gave interesting and important information useful for organic and medicinal chemistry, which are deeply involved in the design and development of new antimalarial agents. The highlights in the preparation of aminoquinoline antimalarials, their protocols and antiplasmodial activity and, specially, the development on hybridization approaches are represented. |
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Authors:
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Vladimir V Kouznetsov; Alicia Gómez-Barrio |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2009-03-03 |
Journal Detail:
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Title: European journal of medicinal chemistry Volume: 44 ISSN: 1768-3254 ISO Abbreviation: Eur J Med Chem Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-05-18 Completed Date: 2009-07-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0420510 Medline TA: Eur J Med Chem Country: France |
Other Details:
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Languages: eng Pagination: 3091-113 Citation Subset: IM |
Affiliation:
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Laboratorio de Química Orgánica y Biomolecular, Universidad Industrial de Santander, Bucaramanga, Colombia. kouznet@uis.edu.co |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aminoquinolines
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chemical synthesis*,
chemistry,
pharmacology* Animals Antimalarials / chemical synthesis*, chemistry, pharmacology* Drug Design* Humans Plasmodium / drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Aminoquinolines; 0/Antimalarials |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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