Document Detail

Recent development in [1,4]benzodiazepines as potent anticancer agents: a review.
MedLine Citation:
PMID:  25311001     Owner:  NLM     Status:  In-Data-Review    
The [1,4]benzodiazepine is an important class of heterocyclic compounds and clinically used for many ailments in humans. The [1,4]benzodiazepine has unique structure that mimics the peptide linkage. This interesting observation completely shifted the interest of medicinal chemist for [1,4]benzodiazepine from CNS acting drugs to anticancer agents. During last few decades, a large number of reports have appeared in the literature highlighting the anticancer activity of [1,4]benzodiazepines. Here, in this article, we have discussed the brief synthesis, origin of [1,4]benzodiazepines as anticancer agent, their mechanism of action and latest developments in this field. We have compiled the most important literature reports from last few decades till date.
Rupinder Kaur Gill; Shiv Om Kaushik; Jasreen Chugh; Sumit Bansal; Anamik Shah; Jitender Bariwal
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mini reviews in medicinal chemistry     Volume:  14     ISSN:  1875-5607     ISO Abbreviation:  Mini Rev Med Chem     Publication Date:  2014  
Date Detail:
Created Date:  2014-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101094212     Medline TA:  Mini Rev Med Chem     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  229-56     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Term Breech Deliveries in the Netherlands.
Next Document:  High occupational physical activity and risk of ischaemic heart disease in women: The interplay with...