Document Detail

Recent advances in isocyanide insertion chemistry.
MedLine Citation:
PMID:  23456037     Owner:  NLM     Status:  Publisher    
As valuable C1 building blocks, isocyanides represent an important class of reactive species and synthons. During the past decades, exhaustive efforts have been devoted to the discovery of highly efficient reactions involving isocyanide on the basis of the development of the Passerini and Ugi reactions. Several types of reactions involving isocyanides have been reported, such as nucleophilic attack, electrophilic addition, imidoylation reactions, and oxidation etc. In this review, recent progress in isocyanide insertion chemistry is presented. Among all isocyanide insertions, two catalytic systems have been developed, that is, Lewis (Brønsted) acid-catalyzed isocyanide insertions and transition-metal-enabled isocyanide insertions, respectively. This review is hence written in the sequence of Lewis (Brønsted) acid-catalyzed isocyanide insertion and transitional metal-enabled isocyanide insertion, where isocyanide insertion into heteroatom-hydrogen bonds, carbon-halogen bonds, carbon-hydrogen bonds, and metal carbenes are summarized.
Guanyinsheng Qiu; Qiuping Ding; Jie Wu
Related Documents :
9720307 - Dinuclear palladium(ii) complexes containing two monofunctional [pd(en)(pyridine)cl]+ u...
4067607 - Some mixed-ligand palladium(ii) complexes of 2,2'-bipyridine and amino acids as potenti...
10889327 - Palladium(ii) complexes of ns donor ligandsderived from s-methyl-dithiocarbazate, s-ben...
20067297 - Ordering of pd(2+) and pd(4+) in the mixed-valent palladate kpd(2)o(3).
14348207 - The equilibrium of the reaction catalysed by citrate oxaloacetate-lyase.
17899537 - Electromigration of a heteroconjugated imidazole-acetate complex in acn.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-3-4
Journal Detail:
Title:  Chemical Society reviews     Volume:  -     ISSN:  1460-4744     ISO Abbreviation:  Chem Soc Rev     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-3-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0335405     Medline TA:  Chem Soc Rev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Elevated amyloid-? plaque deposition in dietary selenium-deficient Tg2576 transgenic mice.
Next Document:  Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the P...