Document Detail

Recent advances in intubation and mechanical ventilation.
MedLine Citation:
PMID:  12531069     Owner:  NLM     Status:  MEDLINE    
The ideal care of the critically ill infant or child should demonstrate a seamless service starting with recognition of potential critical illness and initiation of early resuscitative interventions, escalating to advanced life support and skilled transfer to an appropriate location where intensive care can be continued. This article discusses advances in the package of respiratory care commencing with the decision to provide respiratory support, which includes the decision whether or not to intubate, leading to the choice of mechanical ventilatory support mode in the critically ill child. Indications for intubation include protection of the airway, airway toilet and the need for positive pressure support. Respiratory support may not always require additional airway protection or airway toilet. Non-invasive respiratory support includes continuous positive airway pressure, biphasic positive airway pressure, or negative extrathoracic pressure. Recent advances in understanding and management of acute lung injury, such as appropriate use of positive end-expiratory airway pressure, alveolar recruitment manoeuvres, high frequency ventilation and use of inhaled nitric oxide, will be discussed in the light of recent randomised controlled trials providing evidence of benefit.
A R Magnay
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Paediatric respiratory reviews     Volume:  2     ISSN:  1526-0542     ISO Abbreviation:  Paediatr Respir Rev     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2003-01-17     Completed Date:  2004-09-22     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  100898941     Medline TA:  Paediatr Respir Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  184-94     Citation Subset:  IM    
North Staffordshire Hospital NHS Trust, Newcastle Road, Stoke on Trent, Staffordshire ST4 6QG, UK.
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MeSH Terms
Age Factors
Child, Preschool
Critical Care
Infant, Newborn
Intubation, Intratracheal / adverse effects,  methods
Nitric Oxide / therapeutic use
Positive-Pressure Respiration / methods
Respiration, Artificial / instrumentation,  methods*
Respiratory Distress Syndrome, Newborn / diagnosis,  therapy*
Respiratory Insufficiency / diagnosis,  therapy*
Risk Assessment
Sensitivity and Specificity
Severity of Illness Index
Reg. No./Substance:
10102-43-9/Nitric Oxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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