Document Detail


Recent advances in human brown fat physiology.
MedLine Citation:
PMID:  22471225     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Of the two variants of adipose tissue, white fat is traditionally known as a lipid rich tissue which undergoes pathological expansion in obese conditions. To counter the excess accumulation of white fat in states of energy imbalance, the second and unique type of brown fat plays a key role by burning extra energy into heat through a special metabolic pathway. In addition brown fat also plays a vital role in thermoregulation in animals and newborn humans and infants. Recent progress in research areas of these two types of fat tissue has provided compelling evidence to show that they secrete a large number of chemicals that play an important role in body weight control that involves several mechanisms. Brown fat was considered absent in the adult humans until recently. But new techniques have provided ample support for its active existence. Based on the very recent data it has been suggested that brown fat can be a target organ in the treatment of obesity which can lead to exciting and informative outcomes in the future.
Authors:
D V Muralidhara; Krithika D Muralidhara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of physiology and pharmacology     Volume:  55     ISSN:  0019-5499     ISO Abbreviation:  Indian J. Physiol. Pharmacol.     Publication Date:    2011 Jul-Sep
Date Detail:
Created Date:  2012-04-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374707     Medline TA:  Indian J Physiol Pharmacol     Country:  India    
Other Details:
Languages:  eng     Pagination:  197-206     Citation Subset:  IM    
Affiliation:
Department of Physiology, Faculty of Medicine and Health Sciences, University Sultan Zainal Abidin, Kuala Terengganu, Malaysia. diviem@yahoo.com
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