Document Detail


Recent advances in combination treatments for photoaging: review of the literature.
MedLine Citation:
PMID:  20618367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Photoaging of the skin is a condition characterized by a combination of physical findings including dyspigmentation, fine wrinkles, telangiectasias, tactile roughness, and precancerous change. A combination approach, treating these changes in skin pigmentation and texture simultaneously, is often required to ensure patient satisfaction. OBJECTIVE: To review the dermatologic literature on the use of combination treatments in photoaging using Medline. RESULTS: Review of the Medline literature identified 24 studies of combination approaches to photoaging in which physician and patient evaluation of efficacy of the treatment approaches were performed. Ten studies contained histologic evidence that combination approaches to photoaging, including nonablative and ablative laser resurfacing, topical retinoids, and topical photosensizers with lasers and light sources, produced cutaneous repair of photodamaged skin. These studies documented histologic improvement in various features of photodamaged skin, including change in epidermal and dermal thickness and stratum corneum compaction, greater type I and III collagen production, and less sunburn cell and thymine dimer formation after ultraviolet light exposure. CONCLUSIONS: Review of the literature demonstrates the progress of dermatologic science in understanding the cellular and molecular mechanisms of ultraviolet light-induced damage and in the development of novel combination approaches for repair of photodamage and prevention of cutaneous malignancy.
Authors:
Emily P Tierney; C William Hanke
Related Documents :
10209927 - Osteo-nevus of nanta: a case report and review of the japanese literature.
11840587 - Bullous eruptions caused by extravasation of mannitol--a case report.
648167 - Giant cutaneous angiomyxoma.
1760937 - Cutaneous involvement in wegener's granulomatosis.
7738947 - Change in the epidemiology of reiter's syndrome (reactive arthritis) in the post-aids e...
9032877 - Gamma thalamotomy for parkinsonian and other kinds of tremor.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  36     ISSN:  1524-4725     ISO Abbreviation:  Dermatol Surg     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  829-40     Citation Subset:  IM    
Affiliation:
Laser and Skin Surgery Center of Indiana, Carmel, Indiana, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Botulinum Toxin Type A / therapeutic use
Combined Modality Therapy
Cosmetic Techniques*
Dermatologic Agents / therapeutic use
Humans
Laser Therapy
Neuromuscular Agents / therapeutic use
Skin Aging*
Chemical
Reg. No./Substance:
0/Botulinum Toxin Type A; 0/Dermatologic Agents; 0/Neuromuscular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Preoperative chemoradiotherapy for rectal cancer: a comparison between intravenous 5-fluorouracil an...
Next Document:  Use of high-frequency, high-resolution ultrasound before mohs surgery.