Document Detail


Recent advances in the biology of central nervous system tumors.
MedLine Citation:
PMID:  9425557     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The failure of conventional therapies for many malignant brain tumors has led to a search for more promising alternatives. Recent advances have elucidated a variety of biological factors that act to determine the growth and invasiveness of central nervous system tumors. Such factors include aberrations in the regulation of the cell cycle, apoptosis, and interactions with the host microenvironment. Such insights should translate into novel interventions so that more meaningful outcomes can be achieved in patient care in the future.
Authors:
D M Ashley; D D Bigner
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in neurology     Volume:  10     ISSN:  1350-7540     ISO Abbreviation:  Curr. Opin. Neurol.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-03-05     Completed Date:  1998-03-05     Revised Date:  2013-01-18    
Medline Journal Info:
Nlm Unique ID:  9319162     Medline TA:  Curr Opin Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  445-51     Citation Subset:  IM    
Affiliation:
Department of Haematology and Oncology, Royal Children's Hospital, Parkville, Victoria, Australia.
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MeSH Terms
Descriptor/Qualifier:
Animals
Humans
Nervous System Neoplasms / pathology,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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