| Recent topics on pharmacotherapy for amphetamine-type stimulants abuse and dependence. | |
| | |
MedLine Citation:
|
PMID: 21208168 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Abuse of amphetamine-type stimulants (ATS), including amphetamine, methamphetamine (METH), and 3,4-methylenedioxymethamphetamine (MDMA; ecstasy), has become a major public health problem worldwide. Use of these stimulants has significant psychiatric and medical consequences, including psychosis, dependence, overdose, and death. METH abuse in particular is an extremely serious and growing problem in many countries. The development of treatments for METH-related problems is particularly critical for users who experience persistent psychosis, pregnant women and women with children, gay and bisexual men, and users involved in the criminal justice system. However, there are currently no pharmacological treatments for the wide range of symptoms associated with METH-related problems. One of the reasons for this problem is that our knowledge of the cellular and molecular mechanisms underlying the development of METH-induced psychosis and dependence is limited. In this article, we review recent reports on potential pharmacotherapies (naltrexone, minocycline, antioxidants, immunotherapy, and dopaminergic, serotonergic, cholinergic, and GABAergic agents) for the treatment of ATS abusers. |
| | |
Authors:
|
Hongxian Chen; Jin Wu; Jichun Zhang; Kenji Hashimoto |
Related Documents
:
|
7903968 - Self-assembly of symbionin, a chaperonin of intracellular symbiont. 9051908 - Argenteanones c-e and argenteanols b-e, cytotoxic cycloartanes from aglaia argentea. 20461958 - Clinical case report: a multidisciplinary solution to a complex restorative problem and... 11218478 - The occlusal management of maxillary anterior single-unit implant-supported restorations. 15644068 - Patterns of psychological problems in parkinson's disease. 10976498 - Expectations about hearing aids and their relationship to fitting outcome. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Current drug abuse reviews Volume: 3 ISSN: 1874-4745 ISO Abbreviation: Curr Drug Abuse Rev Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2011-02-11 Completed Date: 2011-06-13 Revised Date: 2012-05-07 |
Medline Journal Info:
|
Nlm Unique ID: 101468123 Medline TA: Curr Drug Abuse Rev Country: United Arab Emirates |
Other Details:
|
Languages: eng Pagination: 222-38 Citation Subset: IM |
Affiliation:
|
Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amphetamine-Related Disorders
/
drug therapy* Antioxidants / therapeutic use* Clinical Trials as Topic Humans Immunotherapy / methods* Molecular Structure Psychotropic Drugs / therapeutic use* Synaptic Transmission / drug effects |
| Chemical | |
Reg. No./Substance:
|
0/Antioxidants; 0/Psychotropic Drugs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-b...
Next Document: Behavioral and neurochemical studies in distinct animal models of ethanol's motivational effects.