Document Detail


Recent progress in deciphering the biosynthesis of aspartate-derived amino acids in plants.
MedLine Citation:
PMID:  20019093     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plants are either directly or indirectly the source of most of the essential amino acids in animal diets. Four of these essential amino acids-methionine, threonine, isoleucine, and lysine-are all produced from aspartate via a well studied biosynthesis pathway. Given the nutritional interest in essential amino acids, the aspartate-derived amino acid pathway has been the subject of extensive research. Additionally, several pathway enzymes serve as targets for economically important herbicides, and some of the downstream products are biosynthetic precursors for other essential plant metabolites such as ethylene and S-adenosylmethionine. Recent and ongoing research on the aspartate-derived family of amino acids has identified new enzyme activities, regulatory mechanisms, and in vivo metabolic functions. Together, these discoveries will open up new possibilities for plant metabolic engineering.
Authors:
Georg Jander; Vijay Joshi
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-12-17
Journal Detail:
Title:  Molecular plant     Volume:  3     ISSN:  1674-2052     ISO Abbreviation:  Mol Plant     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-20     Completed Date:  2010-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101465514     Medline TA:  Mol Plant     Country:  England    
Other Details:
Languages:  eng     Pagination:  54-65     Citation Subset:  IM    
Affiliation:
Boyce Thompson Institute for Plant Research, Ithaca, NY 14850, USA. gj32@cornell.edu
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / chemistry,  metabolism*
Arabidopsis / metabolism
Aspartic Acid / chemistry,  metabolism*
Models, Biological
Plants / metabolism*
Chemical
Reg. No./Substance:
0/Amino Acids; 56-84-8/Aspartic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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