| Recent European Food Safety Authority toxicological evaluations of major phthalates used in food contact materials. | |
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MedLine Citation:
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PMID: 19603396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During the 1980s and 1990s, and at the EU level, the Scientific Committee for Food evaluated a number of phthalates that were being used, or were requested for use, as additives in plastics. At this time, peroxisome proliferation was considered as the pivotal effect on which toxicological evaluation of these chemicals was based. At the end of 1990s, a general consensus has been agreed that rodents are highly sensitive to the phenomenon of peroxisome proliferation and that this particular effect should not be used for human risk assessment. Consequently in 2004, it was requested from the newly created European Food Safety Authority to perform a new evaluation of the mainly used phthalates on the basis of existing data. This paper summarizes evaluations of butylbenzylphthalate, dibutylphthalate, diethylhexylphthalate. |
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Authors:
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Jean-Claude Lhuguenot |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Molecular nutrition & food research Volume: 53 ISSN: 1613-4133 ISO Abbreviation: Mol Nutr Food Res Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-08-03 Completed Date: 2009-10-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231818 Medline TA: Mol Nutr Food Res Country: Germany |
Other Details:
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Languages: eng Pagination: 1063-70 Citation Subset: IM |
Affiliation:
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Ecole Nationale de Biologie Appliquée á la Nutrition et á l'Alimentation (ENSBANA), Université de Bourgogne, 21000-Dijon, France. jc.lhuguenot@wanadoo.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dibutyl Phthalate / toxicity Diethylhexyl Phthalate / toxicity Endpoint Determination Environmental Monitoring Europe Food Packaging* Humans Legislation, Food Phthalic Acids / toxicity* Risk Assessment Safety Species Specificity |
| Chemical | |
Reg. No./Substance:
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0/Phthalic Acids; 117-81-7/Diethylhexyl Phthalate; 84-74-2/Dibutyl Phthalate; 85-68-7/butylbenzyl phthalate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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