| Recent applications of chemiluminescence assays in clinical immunology. | |
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MedLine Citation:
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PMID: 20201791 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Chemiluminescence has traditionally been used to study the nature of the oxidative bactericidal mechanisms of neutrophils and monocytes, the intrinsic defects of abnormally functioning neutrophils or monocytes and cell activation. During the last ten years Chemiluminescence has been applied in a wide variety of techniques including: immunoassays, protein blotting, toxicological and pharmacological tests (e.g. after exposure to antibiotic or immunomodulators agents such as adjuvants and cytotoxic drugs). In this review, we discuss some promising clinical applications of Chemiluminescence in clinical immunology for the study of autoimmune diseases, inflammatory responses, endocrine disorders, immunodeficiency's states, mucosal immune response against drugs and pathogens and host responses against tumors and infections. Further, we review numerous advantages showed by Chemiluminescence-based methods over other methods to assay the same endpoints, which facilitate their uses in the current practice of clinical immunology. |
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Authors:
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A R Rodríguez-Orozco; H Ruiz-Reyes; N Medina-Serriteño |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Mini reviews in medicinal chemistry Volume: 10 ISSN: 1875-5607 ISO Abbreviation: Mini Rev Med Chem Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101094212 Medline TA: Mini Rev Med Chem Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1393-400 Citation Subset: IM |
Affiliation:
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Laboratory of Immunology, Posgraduate Division, Faculty of Medicine Dr. Ignacio Chávez, University of San Nicolás De Hidalgo, Morelia, Michoacán, México. arorozco69@yahoo.com.mx |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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