| Recent Advances of Pyrethroids for Household Use. | |
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MedLine Citation:
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PMID: 22025062 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Development of pyrethroids for household use and recent advances in the syntheses of (1R)-trans-chrysanthemic acid, the acid moiety of most of the household pyrethroids, are reviewed. As another important acid moiety, we discovered norchrysanthemic acid to have a significant vapor action at room temperature when esterified with fluorobenzyl alcohols. In particular, 2,3,5,6-tetrafluoro-4-methoxymethylbenzyl (1R)-trans-norchrysanthemate (metofluthrin) exhibits the highest potency in mosquito coil formulations as well as the vapor action at room temperature against various mosquitoes. Structure-activity relationships of norchrysanthemic acid esters and synthetic studies of norchrysanthemic acid are discussed. |
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Authors:
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Kazuya Ujihara; Tatsuya Mori; Noritada Matsuo |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-25 |
Journal Detail:
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Title: Topics in current chemistry Volume: - ISSN: 0340-1022 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0432204 Medline TA: Top Curr Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Health & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Ltd, 4-2-1 Takatsukasa, Takarazuka, Hyogo, 665-8555, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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