| Recanalization of chronic total coronary arterial occlusions by percutaneous excimer-laser and laser-assisted angioplasty. | |
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MedLine Citation:
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PMID: 2251989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A low primary success and high restenosis rate after recanalization of chronic total occlusions by conventional coronary angioplasty have encouraged the application of new interventional techniques like excimer-laser angioplasty. In 39 patients with a coronary occlusion for 1 to 12 months, recanalization was attempted by laser angioplasty through a multifiber-catheter coupled to a pulsed XeCl excimer laser. After successful passage of the occlusion by a standard guidewire in 27 patients (69%), the laser catheter was advanced over the central guidewire and crossed the occlusion in 25 patients (64%). In 2 patients with unsuccessful passage of the laser catheter, the subsequent attempt with a low profile balloon catheter also failed. In 19 of the 25 patients with successful laser recanalization, the residual stenosis exceeded 50% and was therefore followed by additional balloon angioplasty. The average residual stenosis after laser was 61 +/- 17% of the vessel diameter, and after balloon angioplasty 28 +/- 9% (n = 19), whereas after laser angioplasty alone it was 38 +/- 5% (n = 6). No complications associated with the laser application were observed. Angiographic control after 24 hours showed a reocclusion of 2 (8%) recanalized vessels. In this pilot study, laser angioplasty proved to be a safe and feasible method for the treatment of chronic total coronary occlusions. Because it was necessary to guide the catheter by a central wire, the primary success was limited by a successful passage of the wire of the occlusion. The rate of stand-alone laser angioplasty has to be increased by future improvements of the technique to enable a comparative evaluation of this method with conventional angioplasty. |
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Authors:
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G S Werner; A Buchwald; C Unterberg; E Voth; H Kreuzer; V Wiegand |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 66 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1990 Dec |
Date Detail:
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Created Date: 1991-01-11 Completed Date: 1991-01-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1445-50 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, Georg-August University, Goettingen, Federal Republic of Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Laser* Arterial Occlusive Diseases / surgery* Coronary Angiography Coronary Disease / surgery* Female Humans Male Middle Aged Pilot Projects Recurrence Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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