Document Detail


The rebirth of a phoenix: ovarian cancers are addicted to ErbB-3.
MedLine Citation:
PMID:  20227035     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Several cancer drugs intercept the ErbB family receptors EGFR (ErbB-1) and HER2 (ErbB-2). However, the therapeutic value of targeting ErbB-3 has been less clear. A report in this issue of Cancer Cell by Sheng et al. renews hopes that intercepting ErbB-3-mediated autocrine loops bears potential for treatment of ovarian cancer.
Authors:
Gordon B Mills; Yosef Yarden
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cancer cell     Volume:  17     ISSN:  1878-3686     ISO Abbreviation:  Cancer Cell     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-06-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130617     Medline TA:  Cancer Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  217-8     Citation Subset:  -    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Systems Biology, MD Anderson Cancer Center, Houston, TX 77030, USA. gmills@mdanderson.org
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Comment On:
Cancer Cell. 2010 Mar 16;17(3):298-310   [PMID:  20227043 ]

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