Document Detail

Reassessment of parameters for applying motor-unit triggered stimuli in peri-stimulus time histograms.
MedLine Citation:
PMID:  14568324     Owner:  NLM     Status:  MEDLINE    
We reassessed the response properties of peri-stimulus time histograms (PSTHs) in cases when a test stimulus was triggered by a motor-unit discharge with a constant delay time. In this experiment, single motor unit action potentials were recorded from the right tibialis anterior (TA) muscle of five healthy persons. A test stimulus of the common peroneal nerve with low intensity to activate only Ia afferents of the TA was applied through a bipolar stimulating electrode placed distal to the neck of the fibula. We obtained several PSTHs with various delay times and stimulus intensities in the same recording session for maintaining the background property as the same among the test situations. As a result, we confirmed three characteristics of PSTHs from observed data: (1) given the same delay time (the same background firing properties), a weaker stimulus intensity evokes a lessened effect on PSTHs, naturally; (2) delay time alters the induction balance of direct and indirect effects on PSTHs even if the stimulus intensity is the same because the background firing properties are different; and (3) response probabilities do not correspond directly to stimulus intensities when background firing properties are different; it is possible for a relatively strong intensity stimulus to produce a weaker effect than a weak stimulus. We concluded that comparisons of effects taken at different phases in the control distribution (and also effects taken from different control distributions or different motor units) can be misleading. Therefore, such comparisons should only be made within data obtained from the same phase in the same control distribution of the same motor unit.
Junichi Ushiba; Yasuhiro Kagamihara; Yoshihisa Masakado
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Brain research     Volume:  990     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-10-21     Completed Date:  2004-01-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  8-19     Citation Subset:  IM    
School of Fundamental Science and Technology, Graduate School of Keio University, Room 309, Building 26, 3-14-1 Hiyoshi, Kohoku, Yokohama, Kanagawa, 223-8522, Japan.
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MeSH Terms
Data Display
Electric Stimulation
Evoked Potentials / physiology
Excitatory Postsynaptic Potentials / physiology*
Leg / innervation,  physiology
Motor Neurons / physiology*
Muscle, Skeletal / cytology,  innervation,  physiology*

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