Document Detail

Reassessment of the diagnostic value of the vectorcardiogram in cystic fibrosis (correlation with clinical score, pulmonary function tests and echocardiogram).
MedLine Citation:
PMID:  856599     Owner:  NLM     Status:  MEDLINE    
In 21 children with cystic fibrosis, the vectorcardiogram (VCG) was correlated with various indices of the severity of the disease. The best correlation was found between (1) the azimuth angle of the spatial QRS loop area, representing the rightward and posterior shift of the main electrical forces, and pulmonary function tests (PFT): FEV1 % predicted (r = -0.671, P less than 0.005) and VC% predicted (r = -0.607, P less than 0.005), and (2) the right ventricular anterior wall index measured echocardiographically (r = 0.472, P less than 0.05). More VCG parameters correlated significantly with PFT than with the echocardiogram. This shows the major influence of pulmonary changes on the VCG of those patients. In several subgroups with different clinical scores, the VCG were analyzed and compared to normal limits of age- and sex-matched controls. In this small series, the VCG was a specific but not very sensitive method for predicting the degree of severity of the disease. Echocardiography and vectorcardiography can be considered as two complementary techniques in the evaluation of cystic fibrosis.
C R Brohet; W A Neal; W J Warwick; N Tuna
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardiology     Volume:  5     ISSN:  0301-4711     ISO Abbreviation:  Eur J Cardiol     Publication Date:  1977 May 
Date Detail:
Created Date:  1977-06-11     Completed Date:  1977-06-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404054     Medline TA:  Eur J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  221-38     Citation Subset:  IM    
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MeSH Terms
Cystic Fibrosis / diagnosis*
Forced Expiratory Volume
Peak Expiratory Flow Rate
Respiratory Function Tests*
Vital Capacity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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