Document Detail


Reassessing the standard chest radiograph for intraparenchymal activity.
MedLine Citation:
PMID:  3460397     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The results concerning the activity or inactivity of the alveolitis determined with our proposed scoring system were comparable to those determined with gallium scanning in 68.2% of the patients with biopsy-proven sarcoidosis in our study. Certainly, further evaluation of a larger series of patients over a longer period of time will be required to more adequately evaluate this classification method. We also believe this methodology is reproducible and can be utilized by experienced interpreters of chest radiographs. If we closely reevaluate the 32% of the cases in which the radiographic results disagreed with the gallium assessment of activity, two points worthy of mention become evident. In one group the gallium indices were borderline for activity whereas in the other group the radiographic criteria were most likely indicative of irreversible parenchymal changes. When the radiographs for the latter group were reevaluated for signs of fibrosis such as volume loss, cystic changes, and alteration in vascular patterns, it was possible to delineate a significant false-positive group of patients. We will be reporting the long-term results of our observations over the next several years as well as adding more groups of patients to our initial study analysis. At that time, correlation with all other measurable parameters in determining high-intensity alveolitis versus low-intensity alveolitis will be compared to these new chest radiographic profiles.
Authors:
C E Putman; B Hoeck
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  465     ISSN:  0077-8923     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  1986  
Date Detail:
Created Date:  1986-08-11     Completed Date:  1986-08-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  595-608     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Evaluation Studies as Topic
False Positive Reactions
Female
Gallium Radioisotopes / diagnostic use
Humans
Lung / radiography*,  radionuclide imaging
Lung Diseases / radiography*,  radionuclide imaging
Male
Middle Aged
Sarcoidosis / radiography*,  radionuclide imaging
Chemical
Reg. No./Substance:
0/Gallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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