Document Detail

Reassessing the effects of simple carbohydrates on the serum triglyceride responses to fat meals.
MedLine Citation:
PMID:  3048075     Owner:  NLM     Status:  MEDLINE    
The effects of glucose, sucrose, and fructose ingestion on the serum triglyceride responses to meals containing 40 g fat were studied in 21 normolipidemic, nonobese medical students (9 men, 12 women). Mean postprandial lipemia was not significantly lower after meals containing 50 g glucose and 40 g fat than after meals containing 40 g fat alone (2.11 vs 2.42 mmol.L-1.7 h-1, p greater than 0.45) despite a substantial increase in plasma insulin concentrations after the glucose-containing meal. Ingestion of 50 g fructose and 40 g fat (4.23 mmol.L-1.7 h-1, p less than 0.0001) and 100 g sucrose and 40 g fat (3.77 mmol.L-1.7 h-1, p less than 0.001) resulted in significantly greater lipemia than did the ingestion of fat alone. These findings suggest that the ingestion of insulinogenic carbohydrates does not reduce postprandial lipemia in normolipidemic subjects and that the ingestion of fructose and fructose-containing carbohydrates may augment the postprandial lipemia induced by a fat-containing meal.
J C Cohen; R Schall
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  48     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1988 Oct 
Date Detail:
Created Date:  1988-10-27     Completed Date:  1988-10-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1031-4     Citation Subset:  AIM; IM    
Sport Science Centre, University of Cape Town, South Africa.
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MeSH Terms
Dietary Carbohydrates / pharmacology*
Dietary Fats / metabolism*
Fructose / administration & dosage
Glucose / administration & dosage
Insulin / blood
Sucrose / administration & dosage
Triglycerides / blood*
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Fats; 0/Triglycerides; 11061-68-0/Insulin; 30237-26-4/Fructose; 50-99-7/Glucose; 57-50-1/Sucrose

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