Document Detail

Reasons for ulceration after injection treatment of telangiectasia.
MedLine Citation:
PMID:  11207685     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Sclerotherapy of telangiectasias is widely used for their treatment, but causes skin ulceration in 0.2-1.2% of patients. The cause of this complication is still unclear. OBJECTIVE: We hypothesized that an arteriole is occluded because the sclerosant gets into an arteriovenous (AV) shunt. We have looked for these communications underneath the telangiectasias. METHODS: Doppler examination was performed in 155 cases above the telangiectasias to reveal the presence of an AV shunt. Twenty-two positive sites were excised and histologically screened for AV shunts. RESULTS: Pulsatile sound could be detected by Doppler transducer above spider veins in 112 cases (72.2%). Of the 22 Doppler-positive telangiectasias, 19 AV microshunts could be found histologically. CONCLUSIONS: Understanding the mechanism of this complication can lead to its prevention. No more than 0.2 ml of sclerosant should be administered to a single site. The warning sign of backwash of sclerosant into arterials is the temporary blanching of the skin from the arterial spasm.
I Bihari; Magyar E
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  27     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-06-13     Completed Date:  2001-07-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  133-6     Citation Subset:  IM    
Cardio-Vascular Surgical Department, Semmelweis University, Budapest, Hungary.
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MeSH Terms
Arteriovenous Anastomosis / pathology
Leg / blood supply*
Leg Ulcer / etiology*,  pathology
Middle Aged
Sclerotherapy / adverse effects*
Telangiectasis / therapy*,  ultrasonography
Ultrasonography, Doppler
Comment In:
Dermatol Surg. 2002 Apr;28(4):362   [PMID:  11966802 ]

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