| Rearing rats (Rattus norvegicus) at 30 degrees C does not alter sensitivity to noradrenaline. | |
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MedLine Citation:
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PMID: 2876817 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rats reared from birth at 30 degrees C show a permanent deficit in body temperature regulation. To test the ability of heat-reared rats to respond to an adrenergic drive, carbon dioxide production was measured at five doses of noradrenaline in rats reared at either 20 or 30 degrees C. Noradrenaline-induced carbon dioxide production was greater at all doses in 20 degrees C rats, but sensitivity to noradrenaline was the same in heat-reared and control animals. These findings support the conclusion that the thermoregulatory deficit induced by heat rearing is due to a change induced in the nervous system. |
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Authors:
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N J Dawson; G D Housley; A A Young |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Comparative biochemistry and physiology. A, Comparative physiology Volume: 85 ISSN: 0300-9629 ISO Abbreviation: Comp Biochem Physiol A Comp Physiol Publication Date: 1986 |
Date Detail:
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Created Date: 1986-12-17 Completed Date: 1986-12-17 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 1276312 Medline TA: Comp Biochem Physiol A Comp Physiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 191-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acclimatization
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drug effects* Animals Body Temperature Regulation* / drug effects Carbon Dioxide / metabolism Female Hot Temperature Norepinephrine / pharmacology* Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 51-41-2/Norepinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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