| Real-world management of atrial fibrillation in Internal Medicine units: the FADOI 'FALP' observational study. | |
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MedLine Citation:
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PMID: 21738049 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Atrial fibrillation is the most frequent arrhythmia, but few data are available on patients' characteristics and management in the context of Internal Medicine wards. METHODS: Data were collected at the beginning of 2010 in 18 Internal Medicine units of the regions Liguria and Piemonte (Italy). Each centre reviewed the hospital charts of the last 50 patients discharged during the year 2009 in whom a diagnosis of atrial fibrillation had been made (patient's history or during the hospitalization). RESULTS: A total of 903 atrial fibrillation patients were evaluated. Prevalence of atrial fibrillation among patients hospitalized in Internal Medicine units was 18.2%. More than 85% of patients had at least two diseases other than atrial fibrillation, and 'lone' atrial fibrillation was rare (1.3%). During hospital stay, 80.5% of the patients received at least one treatment for atrial fibrillation: 55.5% received an antithrombotic and 61.8% a drug for arrhythmia, mostly aimed at rate control (47.2%). In-hospital all-cause mortality was 13.4%. At discharge, 70.2 and 68.9% of the patients received prescription of a drug for arrhythmia and for antithrombotic treatment, respectively. Prescription of oral anticoagulants was significantly associated with hypertension, while previous bleeding, age above 75 years, paroxysmal atrial fibrillation, male sex and a number of concomitant drugs of more than four were strong negative predictors. CONCLUSION: Data from our study confirm that atrial fibrillation is a common finding in patients hospitalized in Internal Medicine units, and this population is characterized by multiple comorbidities and severe prognosis. Discrepancies exist between recommendations by guidelines and real-world management, owing to the complexity of patients and limits of existing treatment strategies. |
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Authors:
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Mauro Campanini; Roberto Frediani; Alberto Artom; Giuliano Pinna; Antonella Valerio; Micaela La Regina; Stefania Marengo; Giuliano Lo Pinto; Erica Del Signore; Erminio Bonizzoni; Giovanni Mathieu; Antonino Mazzone; Giorgio Vescovo; |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-6 |
Journal Detail:
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Title: Journal of cardiovascular medicine (Hagerstown, Md.) Volume: - ISSN: 1558-2035 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101259752 Medline TA: J Cardiovasc Med (Hagerstown) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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aDepartment of Internal Medicine, Hospital 'Maggiore della Carità', Novara bDepartment of Internal Medicine, Hospital of Verbania, Verbania cDepartment of Internal Medicine, Hospital 'Santa Corona', Pietra Ligure dFADOI Foundation Research Department, Milan eDepartment of Internal Medicine, Hospital 'S. Andrea', La Spezia fDepartment of Internal Medicine, Hospital 'Mauriziano', Turin gDepartment of Internal Medicine, Hospital 'Galliera', Genoa hDepartment of Internal Medicine, Hospital 'S. Andrea', Vercelli iInstitute of Medical Statistics and Biometry, University of Milano, Milan jDepartment of Internal Medicine, Hospital of Pinerolo, Pinerolo kMedical Department, Hospital of Legnano, Legnano lDepartment of Internal Medicine, Hospital 'San Bortolo', Vicenza, Italy. |
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