| Real-time measurement system for evaluation of the carotid intima-media thickness with a robust edge operator. | |
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MedLine Citation:
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PMID: 18716145 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this report is to describe an automatic real-time system for evaluation of the carotid intima-media thickness (CIMT) characterized by 3 main features: minimal interobserver and intraobserver variability, real-time capabilities, and great robustness against noise. METHODS: One hundred fifty carotid B-mode ultrasound images were used to validate the system. Two skilled operators were involved in the analysis. Agreement with the gold standard, defined as the mean of 2 manual measurements of a skilled operator, and the interobserver and intraobserver variability were quantitatively evaluated by regression analysis and Bland-Altman statistics. RESULTS: The automatic measure of the CIMT showed a mean bias +/- SD of 0.001 +/- 0.035 mm toward the manual measurement. The intraobserver variability, evaluated with Bland-Altman plots, showed a bias that was not significantly different from 0, whereas the SD of the differences was greater in the manual analysis (0.038 mm) than in the automatic analysis (0.006 mm). For interobserver variability, the automatic measurement had a bias that was not significantly different from 0, with a satisfactory SD of the differences (0.01 mm), whereas in the manual measurement, a little bias was present (0.012 mm), and the SD of the differences was noticeably greater (0.044 mm). CONCLUSIONS: The CIMT has been accepted as a noninvasive marker of early vascular alteration. At present, the manual approach is largely used to estimate CIMT values. However, that method is highly operator dependent and time-consuming. For these reasons, we developed a new system for the CIMT measurement that conjugates precision with real-time analysis, thus providing considerable advantages in clinical practice. |
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Authors:
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Francesco Faita; Vincenzo Gemignani; Elisabetta Bianchini; Chiara Giannarelli; Lorenzo Ghiadoni; Marcello Demi |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine Volume: 27 ISSN: 1550-9613 ISO Abbreviation: J Ultrasound Med Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-21 Completed Date: 2008-11-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211547 Medline TA: J Ultrasound Med Country: United States |
Other Details:
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Languages: eng Pagination: 1353-61 Citation Subset: IM |
Affiliation:
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Institute of Clinical Physiology, National Research Council, Pisa, Italy. f.faita@ifc.cnr.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carotid Arteries / ultrasonography* Computer Systems Female Humans Image Interpretation, Computer-Assisted / methods* Male Middle Aged Pattern Recognition, Automated / methods* Reference Values Tunica Intima / ultrasonography* Tunica Media / ultrasonography* Ultrasonography / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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