Document Detail


Real-time detection of deoxyribonucleic acid bases via their negative differential conductance signature.
MedLine Citation:
PMID:  19792183     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
In this Brief Report, we present a method for the real-time detection of the bases of the deoxyribonucleic acid using their signatures in negative differential conductance measurements. The present methods of electronic detection of deoxyribonucleic acid bases are based on a statistical analysis because the electrical currents of the four bases are weak and do not differ significantly from one base to another. In contrast, we analyze a device that combines the accumulated knowledge in nanopore and scanning tunneling detection and which is able to provide very distinctive electronic signatures for the four bases.
Authors:
D Dragoman; M Dragoman
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Publication Detail:
Type:  Journal Article     Date:  2009-08-25
Journal Detail:
Title:  Physical review. E, Statistical, nonlinear, and soft matter physics     Volume:  80     ISSN:  1539-3755     ISO Abbreviation:  Phys Rev E Stat Nonlin Soft Matter Phys     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-10-01     Completed Date:  2009-11-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136452     Medline TA:  Phys Rev E Stat Nonlin Soft Matter Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  022901     Citation Subset:  -    
Affiliation:
Physics Department, University of Bucharest, P.O. Box MG-11, 077125 Bucharest, Romania.
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