Document Detail


Real time 3D (4D) ultrasound-guided percutaneous biopsy of solid tumours.
MedLine Citation:
PMID:  16710817     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The aim of the current study was to investigate the feasibility of real-time 3D (4D) ultrasound-guided biopsy. MATERIALS AND METHODS: Between 2003 and 2005, 53 patients with suspicious lymph nodes or solid tumours underwent 4D ultrasound-guided core needle biopsy using a 4D US-System (Voluson 730, GE/Kretztechnik, Austria). The results were documented prospectively and compared to a matched series of 53 conventional 2D ultrasound-guided core biopsies. RESULTS: 4D ultrasound-guided biopsy can be performed using multiplanar views or a combination of cross-sectional and rendered images. Assessment of additional 3D images during the biopsy procedure was helpful in 34 % of the cases. In the differentiation of malignant and benign lesions, 4D ultrasound guided biopsy yielded 35 true-positive results, 12 true-negative results and 5 false-negative results. The sensitivity and specificity for the diagnosis of malignancy was 87.5 % and 94.4 %, respectively (control group: 89.5 % and 94.4 %). There was one case of insufficient tissue sampling in the 4D targeting group and 2 cases in the control group. No complications were observed related to the biopsy procedure. CONCLUSIONS: 4D ultrasound-guided biopsy is feasible and can improve visualisation of biopsy procedures by multiplanar display or 3D rendering. Although the accuracy is comparable to that of conventional 2D biopsy, this technique may be helpful for biopsy of lesions with close relation to relevant anatomical structures.
Authors:
H Albrecht; C Stroszczynski; R Felix; M Hünerbein
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Publication Detail:
Type:  Journal Article     Date:  2006-05-19
Journal Detail:
Title:  Ultraschall in der Medizin (Stuttgart, Germany : 1980)     Volume:  27     ISSN:  0172-4614     ISO Abbreviation:  Ultraschall Med     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-23     Completed Date:  2006-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8303585     Medline TA:  Ultraschall Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  324-8     Citation Subset:  IM    
Affiliation:
Department of Surgery and Surgical Oncology, Charité University of Medicine Berlin, Campus Berlin Buch and Helios Hospital, Berlin.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Biopsy / methods*
Humans
Image Processing, Computer-Assisted
Imaging, Three-Dimensional / methods*
Lymph Nodes / pathology,  ultrasonography
Middle Aged
Neoplasms / pathology*,  ultrasonography*
Ultrasonography / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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