Document Detail

Readiness: the state of the science (or the lack thereof).
MedLine Citation:
PMID:  20714831     Owner:  NLM     Status:  MEDLINE    
HIV treatment guidelines state that patients' readiness should be assessed before initiating highly active antiretroviral therapy (HAART) to assure adherence. None of the guidelines provide a way to measure readiness. Therefore, this article sought to review the literature on readiness to determine if there was a viable predictor of adherence. Twenty-seven articles were reviewed. Nine described studies that examined the relationship between a measure of readiness and HAART adherence. No readiness measure demonstrated clinical utility as a predictor of adherence. Study flaws included small sample sizes (only one study >100 patients), short follow-up periods (all ≤1 year and six were ≤5 months, four ≤1 month), measures of readiness that related poorly to adherence, and inconsistent adherence measures (eight different measures were used by the researchers). Neither the guidelines nor the literature will help clinicians judge who should initiate HAART and who should delay treatment.
Richard M Grimes; Deanna E Grimes
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Current HIV/AIDS reports     Volume:  7     ISSN:  1548-3576     ISO Abbreviation:  Curr HIV/AIDS Rep     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-14     Completed Date:  2011-01-11     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  101235661     Medline TA:  Curr HIV/AIDS Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  245-52     Citation Subset:  IM    
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MeSH Terms
Anti-HIV Agents / administration & dosage,  therapeutic use*
Antiretroviral Therapy, Highly Active / psychology
CD4 Lymphocyte Count
Clinical Protocols
HIV Infections / drug therapy*
Health Behavior
Health Knowledge, Attitudes, Practice
Medication Adherence / psychology*
Patient Acceptance of Health Care / psychology*
Patient Participation
Practice Guidelines as Topic
Treatment Refusal*
Grant Support
Reg. No./Substance:
0/Anti-HIV Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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