| Readiness: the state of the science (or the lack thereof). | |
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MedLine Citation:
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PMID: 20714831 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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HIV treatment guidelines state that patients' readiness should be assessed before initiating highly active antiretroviral therapy (HAART) to assure adherence. None of the guidelines provide a way to measure readiness. Therefore, this article sought to review the literature on readiness to determine if there was a viable predictor of adherence. Twenty-seven articles were reviewed. Nine described studies that examined the relationship between a measure of readiness and HAART adherence. No readiness measure demonstrated clinical utility as a predictor of adherence. Study flaws included small sample sizes (only one study >100 patients), short follow-up periods (all ≤1 year and six were ≤5 months, four ≤1 month), measures of readiness that related poorly to adherence, and inconsistent adherence measures (eight different measures were used by the researchers). Neither the guidelines nor the literature will help clinicians judge who should initiate HAART and who should delay treatment. |
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Authors:
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Richard M Grimes; Deanna E Grimes |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Current HIV/AIDS reports Volume: 7 ISSN: 1548-3576 ISO Abbreviation: Curr HIV/AIDS Rep Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-09-14 Completed Date: 2011-01-11 Revised Date: 2011-11-01 |
Medline Journal Info:
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Nlm Unique ID: 101235661 Medline TA: Curr HIV/AIDS Rep Country: United States |
Other Details:
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Languages: eng Pagination: 245-52 Citation Subset: IM |
Affiliation:
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Division of General Medicine, Department of Medicine, Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA. Richard.M.Grimes@uth.tmc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-HIV Agents
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administration & dosage,
therapeutic use* Antiretroviral Therapy, Highly Active / psychology CD4 Lymphocyte Count Clinical Protocols HIV HIV Infections / drug therapy* Health Behavior Health Knowledge, Attitudes, Practice Humans Medication Adherence / psychology* Patient Acceptance of Health Care / psychology* Patient Participation Practice Guidelines as Topic Treatment Refusal* |
| Grant Support | |
ID/Acronym/Agency:
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AI036211/AI/NIAID NIH HHS; P30 AI036211-15/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Anti-HIV Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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