Document Detail

Reader performance in radiographic diagnosis of signs of mitral regurgitation in cavalier King Charles spaniels.
MedLine Citation:
PMID:  19765219     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To measure accuracy and variability of diagnosis by radiography of heart enlargement (HE) and heart failure (HF) in mitral regurgitation (MR). METHODS: Sixteen readers representing four levels of experience evaluated 50 sets of radiographs with varying severity of MR for presence or absence of HE, left atrial enlargement (LAE) and HF. The performance of the readers was compared with a reference standard, using area under the curve (AUC) of receiver operating characteristic (ROC) curves. The interreader agreement value kappa (K) was calculated. A subset of difficult cases of HF was analysed before and after removing an outlying reader from each group. RESULTS: AUC for HE was 0.89, for LAE it was 0.93 and for HF it was 0.92. Experience increased certainty of diagnosis but not accuracy. K ranges were HE, 0.53 to 0.67; LAE, 0.61 to 0.69 and HF, 0.49 to 0.58. When only difficult cases of HF were read, accuracy decreased and experienced readers performed better than inexperienced. When outlying readers were excluded, the differences between experienced and inexperienced readers increased. CLINICAL SIGNIFICANCE: LAE, not HE, should be used to evaluate the heart size and indirectly the severity of MR on radiographs. For HF, agreement among individual readers was only moderate. Studies of reader accuracy should consider the effects of interreader variability.
K Hansson; J H?ggstr?m; C Kvart; P Lord
Related Documents :
23652249 - A technique to use ct images for in vivo detection and quantification of the spatial di...
22979909 - Morphometry and magnetic resonance imaging of anterior cruciate ligament and measuremen...
24042579 - Teaching neuroimages: polymyalgia rheumatica and giant cell arteritis.
3880389 - Variability of serial ct scans in subacute necrotizing encephalomyelopathy (leigh disea...
24081969 - Teaching neuroimages: manganese neurotoxicity of the basal ganglia and thalamus.
22922039 - Radioembolization with infusion of yttrium-90 microspheres into a right inferior phreni...
22791559 - An improved coverage and spatial resolution-using dual injection dynamic contrast-enhan...
21048289 - A method for fat suppression in mri based on diffusion-weighted imaging.
9442129 - Transient uterine contraction mimicking adenomyosis on mri.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of small animal practice     Volume:  50 Suppl 1     ISSN:  1748-5827     ISO Abbreviation:  J Small Anim Pract     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-21     Completed Date:  2009-12-07     Revised Date:  2010-02-12    
Medline Journal Info:
Nlm Unique ID:  0165053     Medline TA:  J Small Anim Pract     Country:  England    
Other Details:
Languages:  eng     Pagination:  44-53     Citation Subset:  IM    
Department of Clinical Sciences and Department of Animal Physiology, Swedish University of Agricultural Sciences, Box 7054, SE-750 07 Uppsala, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cardiomegaly / radiography,  veterinary
Dog Diseases / radiography*
Heart Failure / radiography,  veterinary
Mitral Valve Insufficiency / radiography,  veterinary*
Observer Variation*
ROC Curve
Reference Standards
Erratum In:
J Small Anim Pract. 2009 Dec;50(12):678

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pulmonary arterial hypertension secondary to chronic left-sided cardiac dysfunction in dogs.
Next Document:  Increased bactericidal/permeability increasing protein in patients with cirrhosis.