Document Detail


Reactivity to in vivo marijuana cues among cannabis-dependent adolescents.
MedLine Citation:
PMID:  20851531     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Cannabis dependence is a common but poorly understood condition in adolescents. Marijuana craving has been posited as a potential contributing factor to continued use and relapse, but relatively few studies have focused on the measurement of craving and reactivity to marijuana cues. The present work sought to explore reactivity to marijuana cues within this age group.
METHODS: Thirty treatment-seeking cannabis-dependent adolescents (age 13-20) completed a cue reactivity session, consisting of exposure to and manipulation of in vivo marijuana cues ("joint" and lighter) and matching neutral cues (pencil and eraser), in counterbalanced order. Subjective craving and physiological reactivity were assessed.
RESULTS: Participants demonstrated increased craving and skin conductance reactivity in response to marijuana cues, relative to neutral cues.
CONCLUSION: In vivo marijuana cues appear to elicit significant subjective and physiological reactivity among treatment-seeking cannabis-dependent adolescents. Further work is needed with a larger sample and with a wider variety of cues.
Authors:
Kevin M Gray; Steven D LaRowe; Noreen L Watson; Matthew J Carpenter
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-09-20
Journal Detail:
Title:  Addictive behaviors     Volume:  36     ISSN:  1873-6327     ISO Abbreviation:  Addict Behav     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2010-11-15     Completed Date:  2011-05-11     Revised Date:  2013-05-27    
Medline Journal Info:
Nlm Unique ID:  7603486     Medline TA:  Addict Behav     Country:  England    
Other Details:
Languages:  eng     Pagination:  140-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P.O. Box 250861, Charleston, SC, United States. graykm@musc.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Behavior, Addictive / psychology*
Cues*
Female
Galvanic Skin Response / physiology
Heart Rate / physiology
Humans
Male
Marijuana Abuse / psychology*
Young Adult
Grant Support
ID/Acronym/Agency:
K12 DA000357-08/DA/NIDA NIH HHS; K12DA000357/DA/NIDA NIH HHS; K23 DA020482-04/DA/NIDA NIH HHS; K23 DA020482-05/DA/NIDA NIH HHS; K23DA020482/DA/NIDA NIH HHS; M01 RR001070-31/RR/NCRR NIH HHS; M01RR01070/RR/NCRR NIH HHS; R01 DA026777/DA/NIDA NIH HHS; R01 DA026777-01/DA/NIDA NIH HHS; R01DA026777/DA/NIDA NIH HHS
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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