| Reactivity of the human retinal circulation to darkness: a laser Doppler velocimetry study. | |
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MedLine Citation:
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PMID: 6853099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Bidirectional laser Doppler velocimetry (LDV) and fundus photography were applied to investigate the effects of light and darkness on retinal blood flow. Blood flow had increased by an average of 67% after 5 min of darkness. This increase persisted for periods of darkness as long as 80 min (the longest period tested). The magnitude of this elevation, its time course, and its neutralization by the breathing of 100% O2 suggest that, in vivo, the retina consumes more O2 in the dark than in light. This effect is, most probably, associated with the maintenance of the photoreceptor dark current. LDV in light and darkness may become a useful probe of retinal function. |
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Authors:
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C E Riva; J E Grunwald; B L Petrig |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Investigative ophthalmology & visual science Volume: 24 ISSN: 0146-0404 ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Publication Date: 1983 Jun |
Date Detail:
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Created Date: 1983-07-29 Completed Date: 1983-07-29 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 737-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity Darkness* Humans Lasers / diagnostic use Light Oxygen Consumption Retinal Vessels / physiology* |
| Grant Support | |
ID/Acronym/Agency:
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EYO 0120/EY/NEI NIH HHS; EYO 1242/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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