| Reactivity of the 1,3-β-D-glucan assay during bacteraemia: limited evidence from a prospective study. | |
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MedLine Citation:
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PMID: 22594314 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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There are discrepancies in the retrospective studies published in literature of whether or not bacteraemia could lead to false positivity of 1,3-β-D (BG) glucan assay. We performed, for the first time, a prospective study evaluating the role of bacterial bloodstream infection to the reactivity of BG assay. Twenty-six episodes of bacteraemia that occurred in high-risk haematological patients were included in our study. Consecutive BG levels >80 pg ml(-1) were required for test positivity. Only 2 of 26 patients were BG positive - both with IFDs. Thus, we prospectively did not prove bacteraemia as the source of cross reactivity of BG assay in haematological patients. |
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Authors:
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Zdenek Racil; Iva Kocmanova; Martina Toskova; Jana Winterova; Martina Lengerova; Shira Timilsina; Jiri Mayer |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-18 |
Journal Detail:
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Title: Mycoses Volume: - ISSN: 1439-0507 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8805008 Medline TA: Mycoses Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 Blackwell Verlag GmbH. |
Affiliation:
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Department of Internal Medicine, Hematology and Oncology, Masaryk University and University Hospital Brno, Brno, Czech Republic Department of Microbiology, University Hospital Brno, Brno, Czech Republic CEITEC - Central European Institute of Technology, Masaryk University Brno, Brno, Czech Republic. |
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