Document Detail

Reactive thrombocytosis: an early manifestation of Takayasu arteritis.
MedLine Citation:
PMID:  16357775     Owner:  NLM     Status:  MEDLINE    
A woman with Takayasu arteritis is reported who presented with constitutional symptoms and persistent thrombocytosis documented since 3 years before the diagnosis. Disease-specific symptoms such as arm claudication, transient loss of vision, and self-remitting eye ptosis present at the time were apparently missed, because she is a non-English-speaking Hispanic woman whose history was obtained through an interpreter. Extensive workup done at the time failed to reach a definite etiology. A computed tomography scan of the chest done because of midthoracic back pain and an elevated erythrocyte sedimentation rate showed circumferential wall thickening and mild surrounding edema throughout the thoracic and abdominal aorta and both carotid arteries consistent with Takayasu arteritis. Prednisone at a dosage of 1 mg/kg twice a day decreased the platelet count within 45 days of its initiation. Takayasu arteritis should be considered in the differential diagnosis of unexplained thrombocytosis, particularly in young women.
Rubén Peredo; Salvador Vilá; Michelle Goñi; Edgar Colón; Grissel Ríos-Solá
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases     Volume:  11     ISSN:  1076-1608     ISO Abbreviation:  J Clin Rheumatol     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-12-16     Completed Date:  2006-02-07     Revised Date:  2008-04-10    
Medline Journal Info:
Nlm Unique ID:  9518034     Medline TA:  J Clin Rheumatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  270-3     Citation Subset:  IM    
Department of Internal Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
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MeSH Terms
Blood Sedimentation
Glucocorticoids / therapeutic use
Prednisone / therapeutic use
Radiography, Thoracic
Takayasu Arteritis / diagnosis*,  drug therapy
Thrombocytosis / drug therapy,  etiology*
Reg. No./Substance:
0/Glucocorticoids; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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