Document Detail

Reactive lymphoid hyperplasia of liver coexisting with chronic thyroiditis: radiographical characteristics of the disorder.
MedLine Citation:
PMID:  10029298     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Reactive lymphoid hyperplasia of the liver is an extremely rare entity, with six cases reported so far. METHODS: We encountered a 47-year-old Japanese female with reactive lymphoid hyperplasia of the liver, which coexisted with chronic thyroiditis. The lesion was discovered incidentally as a hypo-echoic mass with a hyper-echoic rim at a routine ultrasonography examination. It increased from 12 to 17 mm diameter in 6 months. Radiological studies, such as contrast-enhanced computerized tomography (CT) and angiography demonstrated a hypervascular lesion. RESULTS: It was consequently diagnosed as a neoplasm with malignant potentiality and she underwent partial hepatectomy. The lesion was composed of small mature lymphocytes which formed prominent lymphoid follicles with germinal centres, scattered plasma cells and stromal fibrosis. Immunohistochemical study revealed polyclonal origins of the involved lymphocytes. DNA analysis for the immunoglobulin heavy gene and the T cell receptor beta gene using Southern blot hybridization showed no monoclonality. The following features have characterized the images in past cases, as well as ours: hypo-echoic mass, occasionally with a rim, in ultrasonography and hypervascularity, shown by angiography and enhanced CT.
K Nagano; Y Fukuda; I Nakano; Y Katano; H Toyoda; T Nonami; T Nagasaka; T Hayakawa
Related Documents :
9506198 - Aids-associated secondary lymphoma of bone: a case report with review of the literature.
7808578 - Rounded atelectasis of the lung, just a benign disorder.
16864178 - Nasopharyngeal lymphoid hyperplasia after therapy for childhood lymphomas.
22748958 - Endometriosis of the pancreas.
3015118 - Pigeon herpesvirus: inclusion body hepatitis in a free-ranging pigeon.
18395878 - Fetal genital anomalies: an aid to diagnosis.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of gastroenterology and hepatology     Volume:  14     ISSN:  0815-9319     ISO Abbreviation:  J. Gastroenterol. Hepatol.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-04-21     Completed Date:  1999-04-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8607909     Medline TA:  J Gastroenterol Hepatol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  163-7     Citation Subset:  IM    
Second Department of Internal Medicine, Nagoya University School of Medicine, Aichi, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chronic Disease
Diagnosis, Differential
Follow-Up Studies
Liver Diseases / complications*,  radiography*,  surgery
Middle Aged
Pseudolymphoma / complications*,  radiography*,  surgery
Thyroiditis, Autoimmune / complications*,  radiography
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Sodium butyrate induces alkaline phosphatase gene expression in human hepatoma cells.
Next Document:  Rhabdomyolysis and acute pancreatitis.