| Reactive hyperemic pre-ejection shear stress of brachial artery determines endothelial function in patients with untreated essential hypertension. | |
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MedLine Citation:
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PMID: 17188375 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to identify which phase of wall shear stress (SS) augmentation during reactive hyperemia (RH) is the crucial determinant of endothelial reactivity. Fifty-three patients with untreated essential hypertension were enrolled. A 7.5-MHz linear array transducer was used to record the 2D images and Doppler flow signals of brachial artery at baseline and during RH. Wall SS and flow-mediated vasodilation were calculated sequentially. The result of this study demonstrated that augmentation of wall SS at end-diastolic phase during peak RH is the main rheologic determinant of endothelial function in patients with untreated essential hypertension. |
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Authors:
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Min-Yi Lee; Chih-Sheng Chu; Kun-Tai Lee; Chan-Ming Wu; Sheng-Hsiung Sheu; Wen-Ter Lai |
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Publication Detail:
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Type: Letter Date: 2006-12-22 |
Journal Detail:
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Title: International journal of cardiology Volume: 122 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-10-08 Completed Date: 2007-12-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 68-71 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Flow Velocity / physiology Brachial Artery / physiopathology* Endothelium, Vascular / physiopathology* Female Humans Hyperemia / physiopathology* Hypertension / physiopathology* Male Middle Aged Shear Strength* Vasodilation / physiology* |
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