Document Detail


Reactive hyperemia as an indicator of peripheral vasodilation associated with arterial stenoses.
MedLine Citation:
PMID:  7076439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reactive hyperemia occurs when an artery is temporarily occluded and the occlusion is then released. During a period of vascular occlusion, peripheral vascular dilatation develops distally, and is reversed only gradually after release of the occlusion. Reactive hyperemia was measured in the hind limbs of five mongrel dogs at different degrees of arterial stenosis to determine at what degree of stenosis compensatory vasodilatation of the peripheral vascular bed occurs. In the hind limbs of the dogs, which had been anesthetized, reactive hyperemia as an expression of peripheral vasodilatation did not occur until the critical stenosis (the stenosis at which resting flow started to drop) was reached. It began to occur only beyond the critical stenosis, and then increased as the vessel became totally occluded. This study contradicted the vasodilator reserve theory, which states that during progressive arterial stenosis the peripheral vascular bed dilates to maintain flow until the peripheral vascular bed is maximally dilated, when the critical stenosis is reached.
Authors:
C F Beckmann; D C Levin; R Kubicka
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative radiology     Volume:  17     ISSN:  0020-9996     ISO Abbreviation:  Invest Radiol     Publication Date:    1982 Jan-Feb
Date Detail:
Created Date:  1982-07-08     Completed Date:  1982-07-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0045377     Medline TA:  Invest Radiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  77-81     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Constriction
Constriction, Pathologic / physiopathology
Dogs
Hindlimb / blood supply
Hyperemia / physiopathology*
Iliac Artery
Regional Blood Flow
Vasodilation*
Grant Support
ID/Acronym/Agency:
GM 18674/GM/NIGMS NIH HHS; HL 05832/HL/NHLBI NIH HHS; HL 20895/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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