| Reactive hyperaemia in the dog heart: inter-relations between adenosine, ATP, and aminophylline and the effect of indomethacin. | |
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MedLine Citation:
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PMID: 870195 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intracoronary adenosine, ATP, and the release of an 8 second occlusion increased coronary blood flow (CBF) to a similar extent. Aminophylline decreased the CBF response to adenosine by 80% and that to an 8 s occlusion by 20% but did not change the CBF response to ATP. Indomethacin had no effect on CBF. The results suggest that the increase in CBF after brief occlusions is not mediated in a major way by adenosine or prostaglandins. |
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Authors:
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R W Giles; D E Wilcken |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Cardiovascular research Volume: 11 ISSN: 0008-6363 ISO Abbreviation: Cardiovasc. Res. Publication Date: 1977 Mar |
Date Detail:
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Created Date: 1977-06-30 Completed Date: 1977-06-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0077427 Medline TA: Cardiovasc Res Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 113-21 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine
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antagonists & inhibitors,
pharmacology* Adenosine Triphosphate / pharmacology* Aminophylline / pharmacology* Animals Coronary Circulation / drug effects* Dogs Hyperemia / metabolism* Indomethacin / pharmacology Vasomotor System / drug effects |
| Chemical | |
Reg. No./Substance:
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317-34-0/Aminophylline; 53-86-1/Indomethacin; 56-65-5/Adenosine Triphosphate; 58-61-7/Adenosine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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