Document Detail

Reactive hyperaemia in the dog heart: evidence for a myogenic contribution.
MedLine Citation:
PMID:  832288     Owner:  NLM     Status:  MEDLINE    
Temporary restriction of arterial inflow after release of eight second coronary artery occlusions greatly reduced reactive hyperaemia but prolonged its duration. Early repayment of the flow debt before restriction did not alter these changes. Despite reduced hyperaemia, there was evidence of subendocardial ischaemia during restriction. Yet occlusions of only one and two cardiac cycles produced marked hyperaemia without evidence of post-release subendocardial ischaemia. All these changes were associated with alterations in peripheral coronary artery pressure consistent with myogenic responses contributing to reactive hyperaemia.
R W Giles; E L Wilcken
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular research     Volume:  11     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  1977 Jan 
Date Detail:
Created Date:  1977-03-21     Completed Date:  1977-03-21     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  64-73     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Coronary Circulation
Coronary Vessels / physiopathology
Heart / physiopathology
Hyperemia* / physiopathology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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