Document Detail

Reactive angioendotheliomatosis in association with a well-differentiated angiosarcoma.
MedLine Citation:
PMID:  16148413     Owner:  NLM     Status:  MEDLINE    
A 55-year-old white female with a complex medical history including mixed connective tissue disease and peripheral vascular disease developed a group of red-purple papules on her proximal medial thigh that was followed, five months later, by the development of a large violaceous patch. She reported a history of radiation to this site (for melanoma) during her childhood. She was admitted to the hospital with a presumptive diagnosis of cellulitis, but failed to respond to antibiotics. A biopsy was performed and demonstrated a well-differentiated angiosarcoma arising in conjunction with reactive angioendotheliomatosis. Excision of the lesion was performed, and fifteen months of follow-up have shown no recurrence or metastasis.
Loren E Clarke; Kathleen G Julian; Jennie T Clarke; Michael D Ioffreda
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  27     ISSN:  0193-1091     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-08     Completed Date:  2005-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  422-7     Citation Subset:  IM    
Department of Pathology, The Penn State College of Medicine/Milton S. Hershey Medical Center, Hershey, Pennsylvania 17033, USA.
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MeSH Terms
Cellulitis / diagnosis,  pathology
Diagnosis, Differential
Hemangioma / etiology,  pathology*
Hemangiosarcoma / etiology,  pathology*
Melanoma / pathology,  radiotherapy
Middle Aged
Mixed Connective Tissue Disease / complications
Neoplasms, Radiation-Induced / pathology
Neoplasms, Second Primary / etiology,  pathology*
Peripheral Vascular Diseases / complications
Skin Diseases / etiology,  pathology*
Skin Neoplasms / etiology,  pathology*

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