Document Detail

Reactive sulfur species act as prooxidants in liposomal and skeletal muscle model systems.
MedLine Citation:
PMID:  20175514     Owner:  NLM     Status:  MEDLINE    
Reactive sulfur species (RSS) are redox-active sulfur compounds formed under conditions of oxidative stress that may be capable of initiating oxidation reactions. The objective of this research was to determine if two RSS, sulfite radicals and disulfide S-oxides (DSSO), induce oxidation in n-3 liposomes and muscle homogenates. Sulfite radicals and DSSO caused an increase in secondary oxidation products compared to the unoxidized control within 5 min of addition to liposomes. In muscle homogenates, DSSO caused immediate oxidation of sulfhydryls, whereas sulfite radicals caused a slow and linear oxidation of sulfhydryls and lipid. These results suggest that if conditions exist in muscle foods that promote the formation of RSS, they could be a factor in the course of lipid oxidation by either weakening antioxidant defenses or directly oxidizing lipid molecules.
Robert G Brannan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  58     ISSN:  1520-5118     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-17     Completed Date:  2010-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3767-71     Citation Subset:  IM    
School of Human and Consumer Sciences, Ohio University, W324 Grover Center, Athens, Ohio 45701, USA.
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MeSH Terms
Liposomes / chemistry*
Meat / analysis*
Models, Biological
Muscle, Skeletal / chemistry*
Oxidative Stress
Reactive Oxygen Species / chemistry*
Sulfur / chemistry*
Reg. No./Substance:
0/Liposomes; 0/Reactive Oxygen Species; 7704-34-9/Sulfur

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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