Document Detail


Reactions of transplanted neurocentral synchondroses to different conditions of mechanical stress. A methodological study on the rat.
MedLine Citation:
PMID:  489467     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to elucidate the reactions of neurocentral synchondroses to different forces, the first cervical vertebra of 10 or 25 days old rats was transplanted into sex-matched litter mates. Some vertebrae were transplanted as a whole, in some only the ventral part with its synchondroses was transplanted and, in others the lumen was furnished with an expanding sponge or a spring. The transplantation was done subcutaneously and, in the case of the fragments, intracerebrally as well. The synchondroses of the vertebrae transplanted at 10 days did not differ very much from those of the host 5, 10 or 15 days after the operation, whereas in the vertebrae transplanted at 25 days the synchondroses underwent synostosis earlier than in situ. The synchondroses of the transplanted fragments, and especially of those placed intracerebrally, remained open longer than those in the whole vertebral transplants; the sponge and and the spring also delayed closure. In the synchondroses transplanted at 25 days there was a strong reduction in alcian blue staining, whereas in the spring loaded synchondroses the stainability persisted longer, maybe as an adaptation to the tensile force. It seems that the inherent potential of the neurocentral synchondroses to obliterate at a certain time can be altered by changing the biomechanical conditions.
Authors:
O Rönning; S Kylämarkula
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of anatomy     Volume:  128     ISSN:  0021-8782     ISO Abbreviation:  J. Anat.     Publication Date:  1979 Jun 
Date Detail:
Created Date:  1979-12-20     Completed Date:  1979-12-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0137162     Medline TA:  J Anat     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  789-801     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aging
Animals
Animals, Newborn
Cartilage / growth & development*,  physiology,  transplantation
Cervical Vertebrae / growth & development*,  physiology,  transplantation
Female
Graft Survival
Male
Osteogenesis
Rats
Rats, Inbred Strains
Stress, Mechanical
Transplantation, Homologous
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