Document Detail

Reaction to a surgical implant foreign body masquerading as recurrent uterine sarcoma.
MedLine Citation:
PMID:  21252785     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: : Multiple products to prevent adhesions or lessen the risk of soft tissue attachments are commercially available. The long-term nature of these products is unknown, and they may cause foreign body reactions masquerading as recurrent disease in patients with cancer.
CASE: : A perimenopausal female underwent a hysterectomy and placement of a surgical implant, polylactic acid. Final pathology revealed stage IA low-grade endometrial stromal sarcoma. Areas suspicious for recurrence were noted on radiographic imaging 1 year later, resulting in exploratory surgery. The suspicious areas were found to be foreign body reactions. Mass spectrometry identified the main component of the reactions as polylactic acid.
CONCLUSION: : Adhesion barriers and other surgical implants may not always be completely metabolized and should be used with caution in patients with cancer.
Abigail T Shaltz; Charles A Leath; James F Wiedenhoefer; Michael J Sundborg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  117     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  450-2     Citation Subset:  AIM; IM    
From the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, and the Department of Diagnostic Radiology, Brooke Army Medical Center, Fort Sam Houston, Texas; and the Department of Obstetrics and Gynecology, Womack Army Medical Center, Fort Bragg, North Carolina.
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