Document Detail

Ratio of early mitral inflow peak velocity to flow propagation velocity predicts training effects of cardiac rehabilitation in patients after acute myocardial infarction.
MedLine Citation:
PMID:  20411218     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To use the ratio of early mitral inflow peak velocity (E) to mitral flow propagation velocity (FPV) measured in the early phase of myocardial infarction (early phase E/FPV) to evaluate the training effects of 8 weeks' cardiopulmonary rehabilitation in patients post-myocardial infarction.
DESIGN: Single-blinded, randomized control trial.
PARTICIPANTS: Eighty-seven patients with acute myocardial infarction who had undergone primary coronary intervention.
METHODS: Participants were enrolled randomly to either the cardiac rehabilitation or the control group. The rehabilitation group followed an 8-week supervised rehabilitation programme. All patients completed exercise testing and echo- cardiography at both the beginning and at 8-week follow-up.
RESULTS: The value of E/FPV was significantly reduced at 8-week follow-up in the rehabilitation group (p = 0.005). After cardiac rehabilitation, the increase in peak V(O2) (p = 0.002) and cardiac clinical outcome (composition of mortality, cardiac readmission rate, and revascularization rate) (p = 0.001) were significantly greater in patients with an early phase E/FPV < 1.5 than in patients with early phase E/FPV >or= 1.5. There were no significant differences in the increase in peak V (O2) and cardiac clinical outcome in patients with early phase E/FPV >or= 1.5.
CONCLUSION: Early phase E/FPV < 1.5 predicts more beneficial effects of cardiac rehabilitation in post-acute myocardial infarction patients who have undergone primary coronary intervention.
Cheng-Chih Chung; Wei-Chun Huang; Kuan-Rau Chiou; Ko-long Lin; Feng-Yu Kuo; Chin-Chang Cheng; Shih-Hung Hsiao; Chun-Peng Liu
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of rehabilitation medicine     Volume:  42     ISSN:  1651-2081     ISO Abbreviation:  J Rehabil Med     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-22     Completed Date:  2010-04-30     Revised Date:  2014-05-30    
Medline Journal Info:
Nlm Unique ID:  101088169     Medline TA:  J Rehabil Med     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  232-8     Citation Subset:  IM    
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MeSH Terms
Blood Flow Velocity / physiology
Exercise Test
Exercise Therapy
Exercise Tolerance / physiology
Follow-Up Studies
Middle Aged
Mitral Valve / physiopathology
Myocardial Infarction / physiopathology,  rehabilitation*,  therapy
Oxygen Consumption / physiology
Single-Blind Method
Treatment Outcome
Ventricular Function, Left / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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