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The ApoB/ApoA1 ratio is associated with metabolic syndrome and its components in a Chinese population.
MedLine Citation:
PMID:  20213498     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
In this study, we assessed whether the apolipoprotein B/apolipoprotein A1 ratio (ApoB/ApoA1) is related to metabolic syndrome (MS) and its components in an urban Chinese population. A total of 709 community residents were enrolled. Metabolic syndrome was defined according to the International Diabetes Federation definition in 2005. The high ApoB/ApoA1 group was defined as the gender-specific upper quartile of the ApoB/ApoA1 ratio. Insulin resistance (IR) was defined as the upper quartile of Homa-IR. The ApoB/ApoA1 ratio was significantly higher in subjects with MS, compared to those without (p < 0.05). After adjusting for age and gender, subjects with MS (odds ratio [OR] = 3.5) or IR (OR = 2.3) were more likely to be in the high ApoB/ApoA1 group. The ApoB/ApoA1 ratio increased significantly as the number of MS components increased (p < 0.05). Taken together, these data demonstrate that the ApoB/ApoA1 ratio is strongly associated with MS and its components in an urban Chinese population.
Authors:
Li Zhong; Qifu Li; Yuanjuan Jiang; Dan Cheng; Zhoujun Liu; Bangqiong Wang; Rong Luo; Qingfeng Cheng; Hua Qing
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Inflammation     Volume:  33     ISSN:  1573-2576     ISO Abbreviation:  Inflammation     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-10-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600105     Medline TA:  Inflammation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353-8     Citation Subset:  IM    
Affiliation:
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Street, Chongqing, China.
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