Document Detail


Rates for specific birth defects among offspring of Japanese mothers, Hawaii, 1986-2002.
MedLine Citation:
PMID:  16732765     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this investigation was to identify the rates for specific birth defects among the offspring of Japanese mothers in Hawaii and compare them to rates among the offspring of white mothers. Cases were all infants and fetuses with any of 54 specific birth defects born to Japanese and white mothers identified by a population-based birth defects registry in Hawaii. The rates were calculated for both racial groups and comparisons made by calculating the rate ratio and 95% confidence interval. The rates among the offspring of Japanese mothers were substantially higher for four of the birth defects (pulmonary valve atresia and stenosis, anomalous pulmonary venous return, cleft lip with/without cleft palate, small intestinal atresia and stenosis) and substantially lower for five of the birth defects (pyloric stenosis, hypospadias and epispadias, renal agenesis and hypoplasia, obstructive genitourinary defect, syndactyly). After adjusting for maternal age, these significantly elevated or lower rates remained. Moreover, the rate was significantly higher among the offspring of Japanese mothers for anotia/microtia, tetralogy of Fallot, and persistent cloaca and significantly lower for transposition of great arteries. The rates for a number of specific birth defects differed between Japanese and white mothers in Hawaii.
Authors:
Mathias B Forrester; Ruth D Merz
Related Documents :
22907525 - Early inflammatory markers for prediction of cholestasis in very-low-birth-weight infants.
17885135 - The primitive wrist of homo floresiensis and its implications for hominin evolution.
10375365 - Incidence and risk factors for ventricular septal defect in "low risk" neonates.
20890935 - Risk of birth defects increased in multiple births.
416195 - Peripheral total parenteral nutrition for premature infants with the respiratory distre...
24210925 - Hypothermia and early neonatal mortality in preterm infants.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Congenital anomalies     Volume:  46     ISSN:  0914-3505     ISO Abbreviation:  Congenit Anom (Kyoto)     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-30     Completed Date:  2006-07-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9306292     Medline TA:  Congenit Anom (Kyoto)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  76-80     Citation Subset:  IM    
Affiliation:
Hawaii Birth Defects Program, Honolulu, Hawaii 96817-5157, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Asian Continental Ancestry Group
Congenital Abnormalities / epidemiology*,  ethnology
European Continental Ancestry Group
Female
Hawaii
Humans
Japan
Male
Mothers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Molecular approaches to developmental malformations using analogous forms of valproic acid.
Next Document:  Clock mutant mice with Jcl/ICR background shows an impaired learning ability in water maze, but not ...